Jenni grew up in New Albany, OH, a suburb outside of Columbus, OH, where she attended New Albany High School. She then graduated from Harvard with a degree in Molecular and Cellular Biology. After college Jenni moved back to Columbus where she attended medical school at the Ohio State University and did her residency in Pediatrics. She moved to Chicago in 2018 and works as a physician-researcher in Academic General Pediatrics at Ann & Robert H. Lurie Children's Hospital/Northwestern University, where she researches healthcare policy focusing on underserved children and children with medical complexity. Jenni has participated in JUF YLD's LEADS, Mensches in Motion, Phonothons, and Gesher, and she was named to Oy!Chicago's Double Chai in the Chi: Chicago's Jewish 36 Under 36 List in 2019.