CJG Blog

Center for Jewish Genetics blog

It Turns Out Carrier Screening is For Me (And You!)

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By Shira Gerstein, Sarnoff Center Associate Board Member

While my classmates were gathered in the assembly room to get their blood drawn for Jewish carrier testing my senior year of high school, I hung out in the hallway. It’s not that I’m squeamish at the sight of blood. Rather, I superciliously (and falsely, I now know) thought that carrier screening was not for me. After all, I’m only half Jewish.

During my senior year of college, I learned from the Center for Jewish Genetics that I could have a 50% chance of being a carrier for a Jewish genetic disease if my father was a carrier and that one in four Ashkenazi Jews were carriers. Since I knew I wanted to marry someone Jewish, I decided to get screened as a precaution. However, as I had smugly anticipated, my test results came back negative. After all, I’m only half Jewish. 

While shadowing genetic counselors after college, I saw numerous occasions where genetic counselors took significance with patients’ distant Jewish ancestry. I wondered why it mattered if a patient is only one-sixteenth Jewish. I’m not a carrier and after all, I’m only half Jewish.

Then one of my siblings did an extensive carrier screening test. As I had arrogantly anticipated, she was not a carrier for a Jewish genetic disease. But to my surprise, she was found to be a carrier of a genetic disease that is found predominantly among the Amish. After researching our family history, we discovered that our grandmother’s grandfather was Amish! Perhaps, carrier screening is for me. After all, I’m one-sixteenth Amish and half Jewish.

The moral of the story? Even having just one Jewish grandparent or great-grandparent is enough to increase a person’s risk of carrying a Jewish genetic disorder.  Furthermore, while Jewish genetic disorders appear more often in individuals of Jewish descent, anyone can be a carrier of these conditions. This also means that someone with predominantly Jewish ancestry can still be a carrier of "non-Jewish" disorders. 

The Norton & Elaine Sarnoff Center offers an affordable, accessible carrier screening program for Jewish and interfaith couples. The online, on-demand model doesn’t even require a blood draw! For more information, visit jewishgenetics.org.
 


Request for Proposals: Sarnoff Center Carrier Screening Program

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The Norton & Elaine Sarnoff Center for Jewish Genetics is pleased to release a Request for Proposals (RFP) for a medical partner for its carrier screening program. 

Background: 
For many years, the Sarnoff Center has facilitated a carrier screening program for Jewish persons and non-Jewish partners of Jewish persons to increase rates of carrier screening for Tay-Sachs, Canavan disease, Gaucher disease, and other genetic disorders. At the time of this RFP’s release, the Center’s panel includes 56 diseases more common among Ashkenazi and Sephardic Jews, and more than 125 additional pan-ethnic conditions.

In addition to this program, the Center has also worked to make genetic health expertise available and accessible to its constituents through educational programming, publications, and one-on-one consultation. These services relate to both the recessive conditions covered under the screening program, and to other relevant genetic health issues such as BRCA-related hereditary cancers.

In 2015, the Center transitioned away from its previous medical partner and entered into a short-term agreement with an independent genetics practice with the intent to release a competitive RFP for a longer-term collaboration with an appropriate organization.

The Sarnoff Center invites qualified organizations to submit a proposal for a three-year collaborative agreement to serve as its medical provider for its carrier screening program. 

Key Dates: 

  • February 28, 2018: Letters of Intent Due by 11:59 p.m.
  • March 1, 2018: Mandatory Bidder’s Conference
  • March 22, 2018: Application Due by 11:59 p.m.

  • How to Apply:
    The Norton & Elaine Sarnoff Center for Jewish Genetics has an online application process. For more information or to view the full RFP, visit: https://juf.fluidreview.com/res/. To begin an application, visit https://juf.fluidreview.com/ and click “Sign Up” to create a FluidReview account using the name of the staff person who will be the contact person for this RFP. 

    Please Direct Inquiries to:
    Sarah Goldberg
    SarahGoldberg@juf.org
    312.357.4994

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    Affordable, Accessible Genetic Screening in Illinois

    Our affordable, accessible carrier screening program uses advanced technology to provide comprehensive screening for Jewish and interfaith couples. Visit our Get Screened page to learn more and register.